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KMID : 0360319950270040692
Journal of Korean Cancer Research Association
1995 Volume.27 No. 4 p.692 ~ p.695
Acinar Cell Carcinoma of the Pancreas -A case report-
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Abstract
Acinar cell carcinoma in pancreas is uncommon and occurs in less than 2% among the epithelial non-endocrine pancreatic tumors. Acinar cell carcinoma is usually seen in the elderly patients and shows poor prognosis due to frequent metastasis.
A 59 year old man was admitted because of indigestion and abdominal distension. A large, irregular, marginated, heterogeneous and hypodense mass with internal necrosis in pancreas was the characteristic CT feature of acinar cell carcinoma in
pancreas.
Celiac arteriogram showed a central hypovascular mass with sweeping of left gastric artery. Superior mesenteric arteriography showed tortuous neovascularity along the peripheral portion of mass. Gross specimen chowed an ill defined ovoid pink
friable
mass with a portion of necrotic yellow area. Light microscope showed gyriform or glandular pattern devided by fine fibrovascular stroma. The cells have round vesicular nuclei with prominent nucleoli located in relatively basally and abundant
cytoplasm.
Multiple electron-dense cytoplasmic zymogen granules in cytoplasm of the enlarged acinar cells on electron microscope can lead the diagnosis.
We report the CT and angiographic findings of a case of acinar cell carcinoma in pancreas.
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